Wealthiest by Assets Nonprofits in Missouri

Wealthiest by Assets nonprofit rankings for Missouri. 100 organizations with $22.8B in combined revenue. Updated 2026 IRS 990 data.

100Organizations
$22.8BTotal Revenue
$30.7BTotal Assets
85/100Avg Score

Wealthiest by Assets Rankings for Missouri (100)

#OrganizationCityRevenueAssetsScore
1 Greater Horizons Kansas City $2.0B $2.8B 92/100
2 Stowers Resource Management Inc Kansas City $259.9M $2.0B
3 Saint Francis Medical Center Cpe Girardeau $695.1M $1.7B
4 Patterson Family Foundation Kansas City $341.9M $1.5B
5 Patterson Family Foundation Kansas City $1.3B $1.5B 85/100
6 St Vincent Hospital & Health Care Saint Louis $1.5B $1.1B
7 Presence Chicago Hospitals Network Saint Louis $1.2B $1.0B
8 Health Care Foundation Of Greater Kansas City Kansas City $143.3M $944.7M 95/100
9 Mhm Support Services Chesterfield $1.5B $848.9M 75/100
10 Ascension Health Professional And General Liability Self Insurance Saint Louis $335.9M $821.7M
11 Agnesian Healthcare Inc Saint Louis $584.7M $743.4M
12 Central Indiana Health System Cardiac Services Inc Saint Louis $103.1M $732.9M
13 Donald Danforth Plant Science Center Saint Louis $175.2M $625.7M
14 Alexian Brothers Ambulatory Group Saint Louis $84.3M $551.0M
15 Presence St Marys Hospital Presence Central And Suburban Hospitals Net Saint Louis $807.3M $530.0M
16 Columbia St Marys Hospital Milwaukee Inc Saint Louis $662.7M $501.6M
17 Lutheran Senior Services East Brentwood $202.3M $499.9M
18 Community Foundation Of The Ozarks Inc Springfield $153.5M $479.9M
19 Marvin M Schwan Charitable Foundation Earth City $1.5B $459.5M
20 St Marys Health Inc Dba Ascension Saint Louis $689.6M $394.1M
21 Charles K Blandin Residuary Trust 30/15962 Saint Louis $160.3M $382.3M
22 Midway Usa Foundation Inc Columbia $89.7M $359.7M
23 Alexian Brothers Medical Center Saint Louis $482.5M $332.5M
24 Ascension Ne Wisconsin Inc Saint Louis $363.3M $311.9M
25 The Monroe Clinic Inc Saint Louis $237.3M $310.4M
26 Ascension Se Wisconsin Hospital Inc Saint Louis $388.4M $293.3M
27 Ascension Health Saint Louis $525.8M $292.9M
28 Ascension All Saints Hospital Inc Saint Louis $308.2M $282.8M
29 Columbia St Marys Inc Saint Louis $195.4M $266.6M
30 Alexian Brothers Health System Saint Louis $159.4M $262.4M
31 St Alexius Medical Center Saint Louis $378.1M $257.6M
32 Lake Regional Health System Osage Beach $287.7M $255.2M
33 The W W Smith Charitable Trust Saint Louis $28.3M $243.2M
34 John Knox Village Lees Summit $123.4M $228.3M
35 Presence Healthcare Services Saint Louis $164.8M $225.7M
36 Boone Electric Cooperative Columbia $76.4M $224.1M
37 Centene Foundation Saint Louis $7.9M $221.1M 92/100
38 Ascension Borgess Hospital Saint Louis $405.0M $219.8M
39 St Lukes St Vincents Healthcareinc Saint Louis $262.4M $209.7M
40 Seton Family Of Doctors Saint Louis $260.9M $204.9M
41 St Vincent Hospital Foundation Inc Saint Louis $44.8M $200.5M
42 Hope Educational & Research Center Saint Louis $35.0M $193.4M
43 Stowers Institute For Medical Research Kansas City $187.4M $186.7M 92/100
44 Friendship Village Of West County Chesterfield $49.1M $176.0M
45 Mercy Hospital Joplin Joplin $308.7M $174.7M
46 Bellefontaine Cemetery Association Saint Louis $62.0M $170.1M
47 Black River Electric Cooperative Fredericktown $60.0M $167.6M
48 St Marys Hospital Ozaukee Inc Saint Louis $167.7M $162.4M
49 Alexian Brothers Hospital Network Saint Louis $30.9M $153.8M
50 St Vincent Medical Group Inc Saint Louis $315.0M $141.1M
51 Mid America Transplant Services St Louis $125.6M $133.5M
52 St Marys Hospital Saint Louis $123.8M $128.3M
53 Gateway Arch Park Foundation Saint Louis $7.5M $116.2M
54 Crawford Electric Cooperative Inc Bourbon $41.5M $114.7M
55 Teamsters & Employers Welfare Trust Of Illinois Earth City $78.0M $109.4M
56 Dell Childrens Foundation Saint Louis $28.0M $108.9M 90/100
57 Pi Beta Phi Fraternity Housing Corporation Chesterfield $29.7M $98.6M
58 St John Broken Arrow Inc Saint Louis $92.0M $96.0M
59 Wdh Foundation C4 Saint Louis $22.9M $91.7M
60 Umkc Foundation Kansas City $34.6M $91.5M
61 Wheaton Franciscan Healthcare Southeast Wisconsin Inc Saint Louis $35.6M $91.5M
62 Ascension Wisconsin Foundation Inc Saint Louis $10.9M $90.9M
63 Robert K Johnson Foundation Saint Louis $37.5M $89.2M 70/100
64 Presence Care Transformation Corporation Saint Louis $4.3M $87.4M
65 St Vincent Health Inc Saint Louis $123.3M $86.7M
66 Augustine Institute Inc Florissant $70.0M $83.9M 90/100
67 Gateway Foundation Tr Saint Louis $1.6M $82.4M 90/100
68 St Joseph Hospital & Health Center Inc Saint Louis $177.8M $81.8M
69 Cortex Saint Louis $12.3M $81.8M
70 Consolidated Electric Cooperative Mexico $29.4M $75.4M
71 Lutheran Retirement Center Saint Louis $20.6M $75.2M
72 City Academy Inc Saint Louis $14.4M $74.3M
73 Bellwether Foundation Inc Saint Louis $53.1M $73.0M 75/100
74 Ascension Medical Group Fox Valley Wisconsin Inc Saint Louis $118.5M $72.5M
75 Ascension St John Foundation Saint Louis $10.2M $71.7M 85/100
76 Evergy Inc Kansas City $21.0M $71.5M
77 Ascension Medical Group Southeast Wisconsin Inc Saint Louis $255.7M $69.4M
78 Kipp St Louis Saint Louis $55.1M $69.2M 90/100
79 Northwest Foundation Inc Maryville $8.9M $68.9M
80 H & R Block Foundation Kansas City $9.7M $68.3M
81 Lutheran Hillside Village Inc Saint Louis $21.7M $68.1M
82 Missouri Western State University Foundation Inc N00008837 St Joseph $23.3M $67.3M
83 Emil Buehler Perpetual Trust Saint Louis $10.6M $64.6M
84 Ascension St Francis Hospital Inc Saint Louis $124.4M $63.5M
85 Ascension Via Christi Hospital St Teresa Inc Saint Louis $56.4M $63.0M
86 Svh Real Estate Inc Saint Louis $1.2M $62.7M 65/100
87 Acruxkc Kansas City $5.0M $60.0M
88 American Public Works Association Kansas City $39.8M $53.1M
89 Weaverland Financial Aid Of Missouri Inc Memphis $2.9M $52.9M
90 Rediscover Lees Summit $79.1M $51.5M
91 Ascension Living Bethlehem Woods Village Saint Louis $81.8M $51.2M
92 Owasso Medical Facility Inc Saint Louis $42.9M $50.2M 85/100
93 Henry Ford Health Rochester Foundation Saint Louis $2.9M $49.7M
94 Pi Beta Phi Fraternity Chesterfield $13.9M $49.2M
95 Orscheln Industries Foundation Inc Moberly $7.6M $48.5M
96 Skaggs Foundation Branson $13.7M $48.4M
97 Frontier Schools Inc Kansas City $35.4M $47.7M
98 Alexian Brothers Community Services Saint Louis $36.7M $47.2M
99 International Brotherhood Of Elec Workers 683 Health & Welfare Fund Saint Louis $45.3M $46.9M
100 Kansas City United Methodist Retirement Home Inc Kansas City $22.1M $46.8M

Frequently Asked Questions

What are the wealthiest by assets nonprofits in Missouri?

There are 100 nonprofits in Missouri ranked by wealthiest by assets, with $22.8B in combined annual revenue.

How are Missouri nonprofit rankings determined?

Rankings are based on the latest IRS 990 filing data. Nonprofits with the largest asset holdings. Each organization is ranked relative to other Missouri nonprofits.

How do Missouri nonprofits compare nationally?

Missouri has 100 organizations in this ranking category. View the national wealthiest by assets rankings for broader context.

Where can I find more nonprofit data for Missouri?

Visit our Missouri state page for a complete overview of all nonprofits, or explore specific categories and cities within Missouri.

Other Rankings for Missouri

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