Largest by Revenue Nonprofits in Mississippi

Largest by Revenue nonprofit rankings for Mississippi. 100 organizations with $1.0B in combined revenue. Updated 2026 IRS 990 data.

100Organizations
$1.0BTotal Revenue
$2.6BTotal Assets
82/100Avg Score

Largest by Revenue Rankings for Mississippi (100)

#OrganizationCityRevenueAssetsScore
1 University Of Mississippi Foundation Oxford $261.0M $935.7M
2 Mississippi Methodist Hospital Rehabilitation Center Inc Jackson $83.2M $104.9M
3 Monroe Health Services Inc Tupelo $63.4M $52.0M
4 Blue Cross & Blue Shield Of Mississippi Foundation Flowood $38.0M $162.6M 95/100
5 Mississippi Insurance Guaranty Association Flowood $35.8M $111.1M
6 Mississippi University For Women Foundation Columbus $33.2M $69.1M
7 Laird Hospital Inc Union $30.1M $16.4M 75/100
8 Create Foundation Inc Tupelo $26.7M $181.6M
9 Kemper Cah Meridian $22.4M $13.3M
10 Mississippi Blood Services Inc Flowood $21.3M $17.4M
11 Baptist Medical Center Leake Inc Jackson $20.9M $11.4M
12 American Contract Bridge League Inc Horn Lake $18.2M $20.6M 75/100
13 Jackson State University Development Foundation Inc Jackson $15.3M $65.7M
14 Hartfield Academy Inc Flowood $14.3M $34.4M
15 Scott Regional Medical Center Inc Meridian $14.2M $13.6M
16 Mississippi Public Health Institute Ridgeland $12.1M $2.3M
17 Algernon Sydney Sullivan Foundation Oxford $10.6M $15.1M 85/100
18 Mercy House Teen Challenge Georgetown $10.5M $5.2M
19 James W Hood Family Foundation Jackson $9.7M $20.5M 95/100
20 South Central Community Action Agency Jackson $8.8M $2.2M
21 Martha Coker Home Inc Tupelo $8.0M $4.4M 60/100
22 Starkville Academy Starkville $7.9M $16.2M
23 Apelah Inc Ridgeland $7.8M $8.1M 65/100
24 River Hills Club Of Jackson Inc Jackson $7.3M $8.8M 70/100
25 Magnolia Heights School Inc Senatobia $6.3M $16.5M 92/100
26 Mississippi Arts And Entertainment Center Meridian $6.2M $11.5M
27 Habitat For Humanity Of The Mississippi Gulf Coast Inc Gulfport $6.2M $18.0M 70/100
28 W E Walker Foundation Ridgeland $6.1M $16.0M
29 Charles & Cynthia Bell Foundation Vicksburg $6.0M $7.6M
30 Renaissance Community Loan Fund Inc Gulfport $5.9M $66.5M 90/100
31 Foundation For Mississippi History Jackson $5.9M $8.9M 85/100
32 Anderson Physician Alliance Inc Meridian $5.5M $2.7M
33 Childrens Advocacy Centers Of Mississippi Cacm Jackson $5.3M $1.4M
34 Mississippi Childrens Home Services Inc Jackson $5.1M $1.3M 85/100
35 Partnership Foundation Inc Hattiesburg $4.7M $5.0M 55/100
36 Gulf Of Mexico Alliance Ocean Springs $4.5M $10.4M
37 Biloxi Community Development Corp Biloxi $4.5M $31.4M
38 Junior League Of Jackson Keystone Fund Inc Jackson $4.4M $3.3M
39 Emmett Till Interpretive Center Sumner $4.4M $7.3M
40 Mississippi Center For Justice Jackson $4.3M $10.4M 90/100
41 National Association Of Emergency Medical Technicians Ridgeland $4.3M $6.1M
42 Phi Theta Kappa Foundation Jackson $4.3M $17.9M 90/100
43 But God Ministries Madison $4.1M $5.6M
44 Parker Lifeshare Foundation Madison $4.0M $13.8M
45 International Outreach Ministries Inc Hattiesburg $4.0M $2.1M
46 Northstar International Academy Inc Southaven $3.8M $877K
47 St Dominic Health Services Foundation Inc Jackson $3.7M $25.0M
48 Tau Of Chi Omega Fraternity House Corporation Oxford $3.5M $22.1M
49 One Voice Jackson $3.5M $7.5M 90/100
50 Mississippi School Boards Association Clinton $3.4M $11.3M
51 Purvis Grange Foundation Inc Vicksburg $3.3M $21.9M
52 Mississippi S Toughest Kids Foundation Crystal Spgs $3.3M $20.9M
53 Mississippi River Tr Stoneville $3.2M $62.4M
54 Show Mercy Ministries Incorporated Port Gibson $3.2M $1.4M 92/100
55 Meridian Community College Fdn Meridian $3.0M $32.0M
56 Clinton Christian Academy Inc Clinton $3.0M $6.3M
57 R&N Adult Day Care & Youth Center Hollandale $2.9M $1.0M
58 Kappa Kappa Gamma Fraternity Inc Oxford $2.9M $15.6M
59 East Central Mississippi Health Network Incorporated Meridian $2.8M $3.3M 92/100
60 Northeast Mississippi Community College Development Foundation Inc Booneville $2.8M $10.8M
61 Wheeler Frankstown Water Association Inc Wheeler $2.8M $6.3M
62 Open Doors Homeless Coalition Gulfport $2.7M $913K 88/100
63 Little Lighthouse Central Mississippi Inc Jackson $2.7M $2.7M 88/100
64 Powell Foundation Inc Tupelo $2.6M $9.3M
65 Discovery Christian School Florence $2.6M $4.3M
66 The Noblitt Foundation Jackson $2.6M $5.3M
67 Afa Action Inc Tupelo $2.5M $413K 70/100
68 Mha Health Research & Educational Foundation Inc Madison $2.5M $3.6M
69 Metro Community Development Corporation Jackson $2.5M $8.3M 75/100
70 Catch A Dream Foundation Starkville $2.5M $4.8M 92/100
71 Aids Services Coalition Hattiesburg $2.5M $1.4M 90/100
72 Benedict Day School Sumrall $2.5M $4.8M
73 Russell Christian Academy Meridian $2.5M $2.1M
74 B B King Museum And Delta Interpretive Center Indianola $2.5M $10.3M
75 We Will Go Jackson $2.4M $2.2M
76 Warren A Hood Jr Family Foundation Hattiesburg $2.4M $17.3M 85/100
77 Jacobs Well Ministries Inc Poplarville $2.4M $1.6M 85/100
78 Hancock Resource Center Bay St Louis $2.4M $645K
79 Henry Mize Charitable Foundation Inc Tupelo $2.4M $6.6M 85/100
80 Wheaton Foundation Jackson $2.3M $154K 75/100
81 Ware Foundation Madison $2.3M $18.3M
82 Tallahatchie General Hospital Medical Foundation Charleston $2.3M $13.7M
83 Boys & Girls Club Of The Mississippi Delta Greenwood $2.3M $2.5M
84 Ecm Foundation Ridgeland $2.2M $1.6M 95/100
85 Cleveland Music Foundation Inc Cleveland $2.2M $17.1M
86 South Mississippi Housing Anddevelopment Corporation Gulfport $2.1M $20.9M 75/100
87 Kls Medical Services Southaven $2.1M $0
88 Delta Streets Ministries Inc Greenwood $2.1M $6.9M
89 Hope Academy Inc Gulfport $2.0M $5.6M
90 Boys & Girls Clubs Of The Golden Triangle Starkville $2.0M $1.9M
91 Hellfighters International Laurel $2.0M $3.7M 70/100
92 Mooreville Richmond Water Association Inc Mooreville $1.8M $5.5M
93 Reclaimed Project Jackson $1.7M $1.1M
94 International Museum Of Muslim Culture Jackson $1.7M $2.0M
95 South Sunflower County Hospital Foundation Indianola $1.7M $7.3M
96 Forrest General Healthcarefoundation Inc Hattiesburg $1.7M $5.1M 92/100
97 Burdette Family Foundation Pass Chris $1.7M $4.2M
98 Veterans Of Foreign Wars Of The United States Dept Of Mississippi Columbus $1.7M $1.4M
99 Columbus Christian Academy Inc Steens $1.6M $1.9M
100 Aiming For Healthy Families Inc Corinth $1.6M $91K

Frequently Asked Questions

What are the largest by revenue nonprofits in Mississippi?

There are 100 nonprofits in Mississippi ranked by largest by revenue, with $1.0B in combined annual revenue.

How are Mississippi nonprofit rankings determined?

Rankings are based on the latest IRS 990 filing data. The biggest nonprofits ranked by total annual revenue. Each organization is ranked relative to other Mississippi nonprofits.

How do Mississippi nonprofits compare nationally?

Mississippi has 100 organizations in this ranking category. View the national largest by revenue rankings for broader context.

Where can I find more nonprofit data for Mississippi?

Visit our Mississippi state page for a complete overview of all nonprofits, or explore specific categories and cities within Mississippi.

Other Rankings for Mississippi

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