Largest by Revenue Nonprofits in Pennsylvania

Largest by Revenue nonprofit rankings for Pennsylvania. 100 organizations with $107.7B in combined revenue. Updated 2026 IRS 990 data.

100Organizations
$107.7BTotal Revenue
$160.8BTotal Assets
83/100Avg Score

Largest by Revenue Rankings for Pennsylvania (100)

#OrganizationCityRevenueAssetsScore
1 Upmc Pittsburgh $25.7B $11.2B 65/100
2 Trustees Of The University Of Pennsylvania Philadelphia $20.4B $34.0B
3 Milton Hershey School & School Trust Hershey $5.8B $23.4B
4 The Childrens Hospital Of Philadelphia Philadelphia $3.9B $8.1B
5 Lehigh Valley Hospital Allentown $3.8B $3.6B
6 Opportunity Finance Network Philadelphia $2.3B $2.6B 85/100
7 York Hospital York $2.2B $2.6B
8 Temple University Of The Commonwealth System Of Higher Educ Philadelphia $2.2B $4.1B
9 Main Line Hospitals Inc Radnor $1.7B $3.1B
10 Thomas Jefferson University Philadelphia $1.6B $5.1B
11 Lancaster General Hospital Lancaster $1.6B $1.2B
12 St Lukes Hospital Bethlehem $1.6B $3.6B
13 Reading Hospital West Reading $1.5B $1.0B
14 Drexel University Philadelphia $1.5B $2.9B
15 William Penn Foundation Philadelphia $1.2B $3.4B
16 Swarthmore College Swarthmore $1.2B $3.6B
17 Glaxosmithkline Patient Access Programs Foundation Philadelphia $1.1B $85.3M 95/100
18 Geisinger Wyoming Valley Medical Center Danville $1.0B $868.5M
19 Steelworkers Health & Welfare Fund Pittsburgh $922.8M $110.2M
20 Delta Dental Of Pennsylvania Camp Hill $902.0M $468.0M
21 Abington Memorial Hospital Abington $879.5M $747.5M
22 Wellspan Health York $846.0M $697.2M 85/100
23 Kennedy University Hospital Inc Philadelphia $817.2M $1.3B 85/100
24 Project Management Institute Inc Newtown Sq $767.3M $744.5M
25 Acts Retirement Life Communities Inc Ft Washington $711.8M $2.1B
26 American Bible Society Philadelphia $702.0M $767.6M 90/100
27 Jefferson Health Northeast Philadelphia $693.3M $1.6B
28 Chambersburg Hospital York $630.7M $561.5M
29 Saint Josephs University Philadelphia $531.5M $1.6B
30 Chester County Hospital West Chester $507.4M $530.5M
31 Devereux Foundation Villanova $497.6M $263.4M
32 Carpenters Health & Welfare Fund Of Philadelphia And Vicinity Philadelphia $476.0M $502.0M
33 Gettysburg Hospital York $475.8M $555.0M
34 Bryn Mawr College Bryn Mawr $443.3M $1.6B
35 Franklin & Marshall College Lancaster $435.6M $855.8M
36 Childrens Health Care Associates Inc Philadelphia $417.6M $246.8M 75/100
37 St Mary Medical Center Langhorn $411.1M $992.3M
38 Entergy Corp Companies Bargaining Employees Welfare Benefit Trust Pittsburgh $402.6M $442.2M 85/100
39 Widener University Chester $402.2M $406.2M
40 Doylestown Hospital Doylestown $380.7M $450.3M
41 Holy Redeemer Health System Meadowbrook $365.6M $481.7M
42 Dickinson College Carlisle $364.5M $914.0M
43 The American Oncologic Hospital Philadelphia $363.0M $251.7M
44 St Joseph Regional Health Network Hershey $360.1M $169.8M
45 Caring People Alliance Philadelphia $351.9M $41.3M
46 Eastern Atlantic States Carpenters Health Fund Philadelphia $345.2M $997.0M
47 The Good Samaritan Hospital Of Lebanon Pennsylvania York $329.1M $116.4M
48 Resources For Human Development Inc Philadelphia $328.3M $122.2M
49 Penn State Health Holy Spirit Medical Center Hershey $328.3M $211.2M
50 Ephrata Community Hospital York $321.3M $143.3M
51 Regents Of The Mercersburg College Mercersburg $320.9M $605.2M
52 Elwyn Of Pennsylvania And Delaware Elwyn $308.1M $177.1M
53 National Board Of Medical Examiners Philadelphia $291.0M $457.2M
54 Riddle Memorial Hospital Radnor $287.5M $462.2M
55 Philadelphia College Of Osteopathic Medicine Foundation Philadelphia $284.6M $611.3M 85/100
56 St Luke S Hospital Grand View Campus Sellersville $283.0M $455.4M
57 Geisinger Lewistown Hospital Danville $282.0M $161.6M
58 Messiah University Mechanicsburg $273.5M $322.3M
59 Masonic Villages Of The Grand Lodge Of Pennsylvania Elizabethtown $272.1M $1.4B
60 American Society For Testing And Materials Conshohocken $272.0M $506.1M
61 York College Of Pennsylvania York $269.7M $577.8M
62 Bell Atlantic Retiree Life Insurance Plan Trust Pittsburgh $265.2M $194.0M 70/100
63 Sun Coast Nursing Centers Inc Bala Cynwyd $265.0M $430.1M 65/100
64 Gettysburg College Gettysburg $252.9M $661.3M
65 Upmc Pittsburgh $238.9M $113.6M
66 Mercy Catholic Medical Center Of Southeastern Pa Newtown Sq $236.4M $85.5M
67 St Lukes Warren Hospital Inc Bethlehem $233.8M $262.9M 85/100
68 Veba Health Insurance Trust For Non Union Employees Of Keyspan Pittsburgh $231.4M $184.6M 90/100
69 Pennsylvania Property And Casualty Insurance Guaranty Association Philadelphia $230.7M $186.6M
70 Ursinus College Collegeville $230.6M $326.5M
71 Concordia Lutheran Ministries Cabot $228.3M $777.2M 75/100
72 Upmc Pittsburgh $222.3M $151.3M 85/100
73 Academy Of The New Church Bryn Athyn $218.1M $419.1M
74 American Institute For Chartered Property Casualty Underwriters Malvern $215.9M $336.2M
75 Trumark Financial Credit Union Ft Washington $214.9M $3.4B
76 Muhlenberg College Allentown $203.3M $592.2M
77 Geisinger Health Danville $203.2M $2.7B
78 District Council 33 Health Welfare Philadelphia $195.9M $180.3M
79 Operating Engineers Welfare Fund Of Eastern Pa & Delaware Ft Washington $195.2M $243.1M
80 St Lukes Quakertown Hospital Allentown $189.5M $220.5M
81 Arcadia University Glenside $186.0M $242.6M
82 Philadelphia College Of Osteopathic Medicine Philadelphia $184.0M $151.2M
83 Veba Trust For Union Employees Of Keyspan Corporation Pittsburgh $180.4M $2.7B 90/100
84 Keystone Service Systems Inc Harrisburg $180.3M $93.6M
85 Philadelphia Housing Development Corporation Philadelphia $178.2M $147.3M
86 Philadelphia Orchestra Association Philadelphia $175.8M $234.5M
87 Susquehanna University Selinsgrove $174.3M $376.3M
88 Desales University Center Valley $174.3M $252.5M
89 Philadelphia University Philadelphia $173.3M $209.4M
90 Lehigh Valley Hospital Schuykill Allentown $161.7M $152.7M
91 Lebanon Valley College Annville $160.0M $268.8M
92 Woods Services Inc Langhorne $158.2M $110.7M
93 La Salle University Philadelphia $154.4M $243.8M
94 Holy Family University Philadelphia $148.7M $134.9M
95 Waynesboro Hospital York $141.6M $161.4M
96 Philadelphia Museum Of Art Philadelphia $135.6M $1.2B
97 Philadelphia Foundation Philadelphia $131.5M $704.6M
98 Concordia Lutheran Ministriesfoundation Cabot $130.9M $264.2M 95/100
99 Eastern University St Davids $130.5M $121.6M
100 Pennsylvania Professional Liability Joint Underwriting Association Blue Bell $127.7M $381.0M

Frequently Asked Questions

What are the largest by revenue nonprofits in Pennsylvania?

There are 100 nonprofits in Pennsylvania ranked by largest by revenue, with $107.7B in combined annual revenue.

How are Pennsylvania nonprofit rankings determined?

Rankings are based on the latest IRS 990 filing data. The biggest nonprofits ranked by total annual revenue. Each organization is ranked relative to other Pennsylvania nonprofits.

How do Pennsylvania nonprofits compare nationally?

Pennsylvania has 100 organizations in this ranking category. View the national largest by revenue rankings for broader context.

Where can I find more nonprofit data for Pennsylvania?

Visit our Pennsylvania state page for a complete overview of all nonprofits, or explore specific categories and cities within Pennsylvania.

Other Rankings for Pennsylvania

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