Most Efficient Nonprofits in South Carolina

Most Efficient nonprofit rankings for South Carolina. 100 organizations with $423.5M in combined revenue. Updated 2026 IRS 990 data.

100Organizations
$423.5MTotal Revenue
$786.3MTotal Assets
84/100Avg Score

Most Efficient Rankings for South Carolina (100)

#OrganizationCityRevenueAssetsScore
1 American Federation Off Martial Arts Inc Bluffton $275 $1K 30/100
2 Aiken Beekeepers Association Beech Island $0 $0 70/100
3 Academy For Teaching & Learning Of The Chester County School Disrict Chester $3.5M $10.7M 90/100
4 Together Women Rise Greenville $2.3M $1.5M 95/100
5 Alpha Omega Epsilon Sorority Xi Chapter Clemson $0 $0 50/100
6 Lake Murray Titans Baseball Inc Irmo $3K $2K 85/100
7 Making A Difference Charleston $2K $322 85/100
8 Als Association Sc Chapterinc Columbia $0 $0 20/100
9 Almost Home Feline Refuge Inc Mt Pleasant $0 $0 50/100
10 One By One Inc Mt Pleasant $300 $395 85/100
11 Fort Mill School Facilitiescorporation Fort Mill $5.4M $33.2M 90/100
12 4 A Life Foundation Inman $0 $0 70/100
13 Folly Beach Nature Conservancy Inc Folly Beach $24 $365 60/100
14 Charleston County Motorcycle Squad Charleston $2 $4K 40/100
15 Scago Educational Facilities Corporation For Beaufort School Di Beaufort $2.5M $27K 70/100
16 Hilton Head Island All Sports Booster Club Inc Hilton Head $357K $121K 90/100
17 Owings Family Foundation Greer $158K $1.3M 90/100
18 Associated Industries Of South Carolina Foundation Inc Columbia $152K $916K 95/100
19 Dacusville Elementary School Pto Inc Easley $38K $10K 90/100
20 Orphan World Relief Lexington $97K $16K 85/100
21 Brashier Middle College Charter High School Inc Simpsonville $6.2M $5.8M 92/100
22 Health Sciences South Carolina Columbia $4.3M $3.8M 85/100
23 Dennys Employee Disaster Relief Fund Inc Spartanburg $208K $902K 95/100
24 The Parker Miracle House Foundation Inc Sumter $13K $38K 90/100
25 Blythewood High School Band Boosters Blythewood $170K $44K 92/100
26 Five Oaks Academy Pto Inc Simpsonville $183K $139K 90/100
27 Hands Of Christ Charleston $74K $221K 90/100
28 Educational Facilities Corporationfor Lexington School District No 2 West Columbia $2.1M $13.9M 85/100
29 Little League Baseball Inc Easley $29K $19K 90/100
30 Sumter Two School Facilities Inc Sumter $2.7M $39.8M 90/100
31 The Ano Charitable Foundation Trust Okatie $1.1M $1.4M 85/100
32 South Carolina United Methodist Camps And Retreat Ministries Greenville $2.3M $7.4M 85/100
33 Buffalo Soldiers Of South Carolina Florence $28K $12K 85/100
34 Greg Mathis Charter High School N Charleston $1.6M $427K 92/100
35 Center For Scholarship Administration Inc Taylors $1.1M $2.7M 95/100
36 Outreach Farm Inc Pawleys Isl $140K $267K 92/100
37 Upstate Sc Post 0206 Boiling Spgs $954 $741 75/100
38 Mercy In Me Free Medical Clinic Cheraw $83K $377K 85/100
39 Silver Bluff Athletic Booster Club Jackson $142K $127K 92/100
40 Blaney Volunteer Fire Dept Elgin $8K $15K 95/100
41 Susanna Iacovelli Charitable Foundation Inc Greenville $1.5M $10.2M 92/100
42 Orchard House Club Inc Sunset $1.0M $132K 85/100
43 Purcell Fam Charitable Foundation Johns Island $25K $25K 80/100
44 Rural Advancement Fund Of The National Sharecroppers Fund Inc Orangeburg $20K $77K 92/100
45 Jeffrey & S Weingarten Foundation Johns Island $3K $246K 85/100
46 Singer Retires Action Committee Voluntary Emp Bene Assoc Tr Fund Greenville $144K $619K 30/100
47 Hillenbrand Family Foundation Charleston $176K $43K 85/100
48 Michael J Mungo Foundation Inc Irmo $16.0M $34.4M 92/100
49 Greater Columbia Educational Advancement Foundation Columbia $157K $63K 92/100
50 Mirrors Nitelife Inc Spartanburg $114K $24K 92/100
51 Mary Lincoln Johnson Charitable Foundation Hilton Head $196K $1.3M 92/100
52 St Francis Physician Services Inc Greenville $36.9M $123.7M 60/100
53 Vision Educational Center Dillon $68K $18K 85/100
54 Greer Middle College Charter High School Taylors $7.2M $16.3M 85/100
55 Alice Rich Northrop Memorial Camden $92K $878K 85/100
56 Henry M Blackmer Foundation Inc Charleston $829K $2.2M 85/100
57 Lerner Gray Foundation Inc Bluffton $314K $394K 75/100
58 Peter B & Adeline W Ruffin Foundation Inc Kiawah Island $4.5M $3.0M 75/100
59 Pre Law Advisors National Council Clemson $386K $96K 85/100
60 Public Library Foundation Of Beaufort County Beaufort $197K $918K 95/100
61 Scago Educational Facilities Corporation For Sumter 17 School D Sumter $743K $21.4M 75/100
62 Scago Educational Facilities Corporation For Pickens School Dis Easley $22.0M $163.3M 75/100
63 Marsh View Community Organic Farm St Helena Is $358K $258K 92/100
64 Camp Canaan Rock Hill $3.6M $6.5M 95/100
65 The Craig & Vicki Brown Family Foundation Inc Greenville $1.8M $3.7M 85/100
66 Lakeside Middle School Parent Teacher Organization Lexington $11K $20K 85/100
67 Trees Greenville Inc Greenville $950K $640K 92/100
68 Blue Ridge High School Athletic Booster Club Greer $67K $37K 92/100
69 Mauldin Garden Club Mauldin $3K $1 85/100
70 South Carolina Cattlemens Foundation Inc Saluda $79K $54K 90/100
71 Carolina Human Reinvestment Georgetown $541K $189K 85/100
72 Fox Creek High School Inc North Augusta $9.4M $23.0M 92/100
73 Peru Mission Usa Inc Greenville $1.1M $550K 92/100
74 Williamsburg Regional Hospital Foundation Kingstree $72K $248K 85/100
75 Canhope Aiken $74K $107K 92/100
76 Bluffton High School Booster Club Bluffton $272K $132K 95/100
77 Securing Assets For Education Moncks Corner $183.2M $161.0M 75/100
78 Tidswell Family Charitable Foundation Greenville $92K $821K 95/100
79 Ekedahl Family Foundation Inc Hilton Head $204K $56K 85/100
80 Goodworks Inc Chapin $471K $1.6M 92/100
81 Triune Mercy Center Greenville $1.4M $3.7M 95/100
82 South Family Foundation Inc Bluffton $132K $1K 75/100
83 Bradley Family Foundation Johns Island $1 $135K 70/100
84 Carolina Coast Cotillion Murrells Inlt $62K $54K 85/100
85 721 Ministries Inc Columbia $360K $223K 92/100
86 Preservation Tr For Historic St Helenas Church Inc Beaufort $443K $7.5M 95/100
87 Charleston Digital Corridor Foundation Charleston $2.4M $5.0M 95/100
88 Lowcountry Lab Rescue Charleston $52K $13K 85/100
89 Grateful Goldens Rescue Of The Low Country Myrtle Beach $104K $156K 92/100
90 Speak For Animals Greenville $356K $135K 95/100
91 Jeffrey And Jennifer Allred Family Foundation Inc Sullivans Island $159K $106K 85/100
92 Narrow Gate Missions Simpsonville $53K $10K 92/100
93 Vine & Branches Home Educators Myrtle Beach $486K $181K 85/100
94 Guthrie Risk Retention Group Charleston $80.9M $53.9M 75/100
95 Reserve At Lake Keowee Community Foundation Sunset $276K $490K 90/100
96 Allied Services Risk Retention Group Charleston $2.0M $8.0M 85/100
97 Down Syndrome Association Of The Lowcountry Mt Pleasant $93K $428K 95/100
98 George And Ann Helena Howard Foundation Greenville $80K $362K 85/100
99 Kids Of The Arts Inc Mt Pleasant $56K $20K 85/100
100 Upstate Homeschool Co Op Inc Taylors $2.1M $2.4M 92/100

Frequently Asked Questions

What are the most efficient nonprofits in South Carolina?

There are 100 nonprofits in South Carolina ranked by most efficient, with $423.5M in combined annual revenue.

How are South Carolina nonprofit rankings determined?

Rankings are based on the latest IRS 990 filing data. Nonprofits with the best program expense ratios. Each organization is ranked relative to other South Carolina nonprofits.

How do South Carolina nonprofits compare nationally?

South Carolina has 100 organizations in this ranking category. View the national most efficient rankings for broader context.

Where can I find more nonprofit data for South Carolina?

Visit our South Carolina state page for a complete overview of all nonprofits, or explore specific categories and cities within South Carolina.

Other Rankings for South Carolina

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