Best Charities by Program Spending Disease & Disorders Nonprofits in Pennsylvania

Top disease & disorders nonprofits in Pennsylvania ranked by best charities by program spending. View detailed financial data, spending analysis, and mission scores for 100 organizations.

100Organizations
$1.5BRevenue
$1.6BAssets
90/100Avg Score

Pennsylvania is home to 100 disease & disorders nonprofits. When ranked by best charities by program spending, these organizations collectively manage $1.5B in revenue and $1.6B in assets. Always B Smiling Inc leads the ranking with $626K in annual revenue.

Rankings

#OrganizationRevenueAssetsScore
1Always B Smiling Inc$626K$1.3M---
2Keystone Independence Management$3.9M$725K---
3Bucks County Biotechnology Center Inc$6.1M$34.3M85/100
4Once Upon A Preemie Inc$585K$504K---
5Concordia Community Support Services$50.1M$158.1M---
6Association For Comprehensive Energy Psychology$823K$289K---
7Ecog Acrin Medical Research Foundation Inc$53.3M$16.0M---
8Devereux Foundation$497.6M$263.4M---
9Transplant Foundation$13.9M$70.8M---
10Jake Gittlen Memorial Golf Tournament$5.7M$8.1M---
11Sharpe Strumia Research Foundation Of The Bryn Mawr Hospital$1.6M$24.6M95/100
12Partners Foundation$1.1M$3.9M---
13Eagles Autism Challenge Inc$12.1M$10.2M---
14The Abim Foundation$6.8M$91.9M---
15Michaels Way$16.3M$13.0M---
16Southern Chester County Emergency Medical Services Inc$2.3M$1.8M---
17Appendix Cancer Pseudomyxoma Peritonei Research Foundation$777K$2.2M---
18Bringing Hope Home Inc$3.2M$975K---
19Primary Care Services$4.3M$317K---
20Cancer Bridges$2.7M$5.7M---
21Unite For Her$7.0M$5.0M---
22Crescent Foundation$809K$521K---
23Parkinson Foundation Of Western Pennsylvania$847K$150K---
24Cystic Fibrosis Research Fund$3.7M$6.0M---
25Lou Berteotti Foundation$1.0M$1.6M---
26Accessabilities Inc$10.1M$8.1M---
27Community Living And Support Services Inc$12.2M$14.4M---
28Lancaster Cleft Palate Clinic$5.2M$11.2M---
29Alleghenies Unlimited Care Providers$9.0M$17.5M---
30Developmental And Disability Services Of Lebanon Valley$1.1M$1.3M---
31United Disabilities Services$22.8M$39.5M---
32Creating Unlimited Possibilities Inc$809K$1.2M---
33Cerebral Palsy Association Of Chester County Inc$1.7M$2.6M---
34Avenues$7.0M$5.7M---
35Penncares$3.8M$7.0M---
36Main Street Missions Corporation$547K$655K---
37Northeast Regional Cancer Institute$1.5M$4.7M---
38Stanley M Marks Blood Cancer Research Fund$1.1M$761K---
39Fayette Oncology Associates$4.3M$4.5M---
40American Association For Cancer Research Foundation$53.4M$4.8M---
41Kisses For Kyle Foundation$614K$47K---
42Butler Cancer Associates Inc$29.0M$9.2M---
43Upmc St Clair Hospital Cancer Center$9.3M$6.6M---
44Pediatric Cancer Foundation Of The Lehigh Valley Inc$1.2M$1.6M90/100
45Pink Hands Of Hope$592K$402K---
46Chambersburg Health Services$30.1M$52.3M---
47Association Of American Cancer Institutes$2.9M$5.9M---
48Oncology Nursing Foundation$8.0M$20.5M---
49Ronald Mcdonald House Of Danville Inc$1.1M$7.3M---
50Chrysalis Initiative$807K$99K---
51Community Liver Alliance$779K$892K---
52Beyond Celiac$3.4M$5.4M---
53Bucks County Association For The Blind And Visually Impaired$1.6M$9.4M---
54Blair Clearfield Association For The Blind And Visually Impaired$925K$1.8M---
55Lions Eye Bank Of Delaware Valley$5.9M$16.8M---
56Vision Resources Of Central Pennsylvania$15.5M$21.0M---
57Butler County Association For The Blind Incorporated$848K$642K---
58Berks County Association For The Blind Inc$1.4M$3.6M---
59Deaf Hearing Communication Center Inc$6.8M$4.3M---
60Adult Congenital Heart Association Inc$2.0M$1.8M---
61The Heart Group Of Lancaster General Health$18.8M$3.9M---
62Uplifting Athletes Inc$1.2M$285K---
63Alveoli Corporation$965K$746K90/100
64Breathe Pennsylvania$9.4M$35.5M---
65Hepatitis B Foundation$6.2M$20.5M---
66Shining Stars Therapeutic Riding Program Inc$976K$2.5M92/100
67Epilepsy Association Of Western And Central Pa$1.8M$7.4M---
68Spina Bifida Association Of Western Pennsylvania$1.1M$1.2M---
69Dementia Society Inc$10.8M$7.7M---
70United Mitochondrial Disease Foundation Inc$5.0M$6.4M---
71Malaria Consortium Us Inc$12.6M$10.8M---
72Positive Effect Outreach Ministry Inc$1.8M$510K---
73Aids Care Group$70.7M$22.9M---
74Prevention Point Pittsburgh$2.0M$1.5M---
75Action Wellness$16.1M$6.6M---
76Wyoming Valley Aids Council$4.4M$1.5M---
77Allies For Health & Wellbeing$23.3M$7.1M---
78Aids Law Project Of Pennsylvania$1.2M$1.1M---
79Alder Health Services Inc$7.6M$3.1M---
80Ftd Disorders Registry Llc$871K$2.2M---
81Davos Alzheimers Collaborative Inc$9.0M$13.4M---
82Autism Diagnostic Evaluations Resources Services$1.5M$960K---
83Autism Society Of Pittsburgh Inc$575K$702K---
84Pennsylvania Advocates And Resources For Autism And Intellect$1.9M$792K---
85Medical Academy Of Pediatrics And Special Needs$855K$323K---
86Better Outcomes Living Diversely Inc$3.9M$574K---
87Vista Adult Services Organization$6.4M$1.6M---
88Autism Society Northwestern Pennsylvania$750K$1.5M---
89Xel Foundation$563K$512K---
90Merakey Midwest$3.0M$549K---
91Kaleid Ascope$1.7M$1.8M---
92Charcot Marie Tooth Association$6.1M$9.5M85/100
93Grand View Lehigh Valley Health Services$2.8M$1.0M---
94Allegheny School Of Anesthesia$899K$714K---
95Childrens Anesthesiology Associates Ltd$109.2M$95.8M---
96American Board Of Internal Medicine$105.8M$224.3M---
97The Wright Center For Graduate Medical Education$49.1M$37.5M---
98Thinkbig Pediatric Cancer Fund Inc$664K$445K---
99Apraxia Kids$1.3M$652K---
100Service Coordination Unlimited Inc$9.2M$5.6M---

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Frequently Asked Questions

What are the top disease & disorders nonprofits in Pennsylvania?

This page lists 100 disease & disorders nonprofits in Pennsylvania ranked by best charities by program spending. Data comes from IRS 990 filings enriched with AI-driven analysis.

How does Pennsylvania compare to other states?

With 100 disease & disorders organizations and $1.5B in combined revenue, Pennsylvania has a significant disease & disorders nonprofit sector.